JULIO AGUIRRE-GHISO, PhD
Icahn School of Medicine
Targeting Intrinsic And Immune Mechanisms In Persistent Dormant Cancer Cells In Stage IV Breast Cancer
CHARLES CLEVENGER, MD, PhD
Virginia Commonwealth University
Inhibition of breast cancer metastatic outgrowth with non-immunosuppressive cyclosporine
VERA DONNENBERG, PhD
University of Pittsburgh School of Medicine UPMC Hillman Cancer Center
Assays to determine optimal dosing and therapeutic effects of localized immunotherapy for established metastatic breast cancer t
GLORIA ECHEVERRIA, PhD
MD Anderson Cancer Center
Elucidation and functionalization of transcriptomic heterogeneity of established multi-organ metastases in patient-derived xenog
DORRAYA EL-ASHRY, PhD
University of Minnesota School of Medicine
Eliminate breast cancer metastasis by targeting the tumor microenvironment
XU FENG, PhD
University of Alabama at Birmingham
Development of Targeted Drugs for Treating Breast Cancer Bone Metastasis
JANET FUNK, MD
University of Arizona Cancer Center
Improving Survival in Stage IV Breast Cancer by Targeting Dormant Breast Cancer Cells in Bone
ANA GARRIDO-CASTRO, MD
Dana-Farber Cancer Institute
Identifying predictive biomarkers of response to PD-1 inhibition in metastatic triple-negative breast cancer
MARK HEADLEY, PhD
Fred Hutchinson Cancer Research Center
Monocyte Contribution To Lung Metastasis Of Breast Cancer
FRANSISCA LEONARD, PhD
Houston Methodist Hospital Research Institute
CRISPR-nanoparticle for macrophage reprogramming: New therapeutic strategy for breast cancer liver metastasis
SOPHIA LUNT, PhD
Michigan State University
Targeting Sialic Acid Metabolism to Stop Metastatic Breast Cancer
ELIZABETH MCDONALD, MD, PhD
University of Pennsylvania
In vivo visualization and quantification of pharmacodynamics response to PARPi therapy
ERIK NELSON, PhD
University of Illinois
Targeting an immune-suppressive cholesterol metabolite in the treatment metastatic breast cancer
JOSH NEMAN, PhD
University of Southern California
Chemotherapy and tau interplay permeabilize BBB and facilitate brain metastasis
AXEL SCHÖNTHAL, PhD
University of Southern California
Controlled Opening of the Blood-Brain Barrier to Achieve Therapeutic Access of Trastuzumab in HER2-Positive Brain Metastases
BRAD ST CROIX, PhD
National Cancer Institute
Improving Immunotherapies for Advanced Metastatic Breast Cancer
RACHEL STEWART, PhD
University of Kentucky
Characterizing Metastatic Breast Cancer Heterogeneity through Post-Mortem Tissue Collection
WEI TAO, PhD
Harvard Medical School/Brigham and Women’s Hospital
Multi-staged delivery system overcoming the physiological barriers for metastatic breast cancer (MBC) therapy
MICHAEL WENDT, PhD
Purdue University
Enhancing anti-metastatic immunity through targeted inhibition of SHP2 phosphatase
THOMAS WESTBROOK, PhD
Baylor College of Medicine
Microenvironment response disparities of metastatic TNBC to multi-tyrosine kinase inhibition
DIHUA YU, MD, PhD
MD Anderson Cancer Center
Combating Breast Cancer Brain Metastasis by Blocking CDK5 Driver Kinase Function
FIONA YULL, PhD
Vanderbilt School of Medicine
Macrophage-based immunotherapy for eradication of pre-existing breast cancer metastases
DIANA CITTELLY, PhD
University of Colorado Anschutz Medical Campus
Targeting BDNF/TrkB in Brain Metastasis from Young Women with TNBC
MICHAEL FLISTER, PhD
Medical College of Wisconsin
Personalized Therapy for Curing Metastatic Breast Cancer
ANDREI GOGA, MD, PhD
University of California, San Francisco
Targeting the MYC Pathway in Metastatic Breast Cancer
MELANIE HAYDEN GEPHART, MD, MAS
Leland Stanford Junior University
Halting the Progression of Breast Cancer Leptomeningeal Brain Metastases
CHERYL JORCYK, PhD
Boise State University
High Impact Therapeutic for the Elimination of Breast Cancer Metastasis to Bone
JAMES MCINTYRE, MA, PhD AND BARBARA FINGLETON, PhD
Vanderbilt University
A Novel Self-Reporting Paclitaxel Prodrug without Systemic Neurotoxicity: Preclinical Assessment for Targeted Treatment of Metas
VIVEK MITTAL, PhD
Weill Medical College of Cornell University
Targeting Epigenetic Regulator PRC2 as a Therapy for Established Metastasis
PARTHA ROY, PhD
University of Pittsburgh
Pharmacological Inhibition of Myocardin-Family Proteins as a Novel Strategy to Combat Metastatic Breast Cancer
REBECCA WATTERS, PhD
University of Pittsburgh
Discovery of Clinically Actionable Genes in Breast Cancer Bone Metastases
PAULA BOS, PhD
Virginia Commonwealth University
Regulatory T Cell Promotion of Brain Metastatic Processes
IAN CORBIN, PhD
University of Texas Southwestern Medical Center
Lipoprotein Omega-3 Fatty Acid Nanoparticles: A Novel Treatment for Breast Cancer Liver Metastases
KATHLEEN GALLO, PhD
Michigan State University
Deciphering and Targeting Signaling Nodes that Drive Metastatic Breast Cancer
TODD GIORGIO, PhD
Vanderbilt University
Quantitative Characterization of Anti-Tumor Immune Response in Metastatic Breast Cancer Induced by Focused Ultrasound
PATRICIA SHEEAN, PhD, RDN
Loyola University Chicago
Is lean soft tissue (i.e., skeletal muscle) a potentially modifiable biomarker predictive of prognosis, treatment tolerance and
SENDURAI A. MANI, PhD
University of Texas MD Anderson Cancer Center
Targeting Cancer Stem Cells to Treat Metastasis
KATHERINE LOREE COOK, PhD
Wake Forest University
Dietary Considerations Effecting Lung Metastatic Therapeutic Responsiveness and Co-Morbidities
JOSHUA DONALDSON, MD, PhD
Johns Hopkins University
Resistance Mechanisms to Palbociclib in Hormone Positive Metastatic Breast Cancer
GINA SIZEMORE, PhD
Ohio State University
Targeting Novel Tumor-Stroma Interactions in Breast Cancer Brain Metastases
DAVID SOTO-PANTOJA, PhD
Wake Forest School of Medicine Comprehensive Cancer Center
Anti-CD47 Immunotherapy as a Treatment for Metastatic Breast Cancer
KATHRYN SCHWERTFEGER, PhD
University of Minnesota
Development of Immune-based Strategies to Enhance Therapeutic Targeting of Metastatic Breast Cancer
BRAD ST. CROIX, PhD
National Cancer Institute Center for Cancer Research
Improving Therapy for Metastatic Breast Cancer through Targeting of Tumor Stroma
J. CHUCK HARRELL, PhD
Virginia Commonwealth University
Genomic Dissection of Patient-Derived Xenograft Breast Cancer Liver Metastasis Models
YIBIN KANG, PhD
Princeton University
Development of a Humanized Mouse Model of Breast Cancer Liver Metastasis
YIBIN KANG, PhD
Princeton University
Sensitizing Bone Metastasis to Chemotherapy and Radiotherapy by Targeting Jagged1-Mediated Tumor-Stromal Interactions
BONNIE KING, PhD and CHRISTOPHER CONTAG, PhD
Stanford University
Modeling Therapeutic Strategies for Breast Cancer Metastasis to Bone
JITESH PRATAP, PhD
Department of Anatomy & Cell Biology
Novel Regulatory Mechanisms of Cell Survival During Bone Metastasis of Breast Cancer
TIFFANY SEAGROVES, PhD
University of Tennesee Health Science Center
Targeting Creatine Kinases to Inhibit Metastatic Breast Cancer
GEORGE SGOUROS, PhD
Johns Hopkins University, School of Medicine
A Pre-Clinical Model of anti-HER2/neu-Antibody Reactive Breast Cancer Metastases
HAIFA SHEN, PhD, MD
Houston Methodist Research Institute
Harnessing Vascular and Cellular Depots of Nanotherapeutics for the Treatment of Metastatic Breast Cancer
KAY-UWE WAGNER, Phd
University of Nebraska Medical Center
Identification of Candidate Target Genes for Metastasis and Cancer Cell Dormancy in a Novel Triple-Negative Breast Cancer Model
MICHAEL WENDT, PhD
Purdue University Center for Cancer Research
Targeting Growth-Factor Receptor Discordant Metastatic Breast Cancer
ELIZABETH YEH, PhD
Medical University of South Carolina
Application of a Connexin 43 (Cx43) Targeted Agent for the Treatment of Metastatic Breast Cancer
SWARNALI ACHARYYA, PhD
Institute for Cancer Genetics, Columbia University
Reactivating anti-tumor granulocytic cells to provoke immune attack against breast cancer metastasis
Eran Andrechek, Ph.D.
Michigan State University
Identification of driver mutations that regulate metastasis
BALAMURUGAN KUPPUSAMY, PhD
NCI/NIH
This METAvivor funded grant has been accepted and in online as preview in Journal of Clinical Investigation Insight.
https://insight.jci.org/in-press-preview
Inflammatory Breast Cancer: Role of the CEBPD-FBXW7 Signaling Pathway
WILLIAM SCHIEMANN, PhD
Case Western Reserve University
Implementing a Forward Genetic Screen to Identify Novel Proto-Oncogenes Operant in Overcoming Metastatic Dormancy
SOFIA MERAJVER, MD
University of Michigan Comprehensive Cancer Center
Engineering cancer metastases platforms for precise medicine
DOUGLAS HURST, Ph.D.
University of Alabama at Birmingham, Alabama
Improving oncolytic herpes simplex virus for metastatic breast cancer
DAVID LUM, Ph.D.
Oklahoma Medical Research Foundation
Validation of patient-derived breast tumor grafts as predictors of tumor evolution and drug resistance
DIHUA YU, M.D., Ph.D.
The University of Texas MD Anderson Cancer Center
Identification and Targeting of Kinases Involved in Breast Cancer Brain Metastasis
CANDECE L. GLADSON, M.D.
Cleveland Clinic
FIP200 promotes survival through autophagy of metastatic breast cancer in the brain
HEIDE L. FORD, PH.D.
University of Colorado School of Medicine
Understanding the Role of miR106b-25 in Breast Cancer Associated Metastasis: A potential new metastasis therapy
RAHUL JANDIAL, MD, PHD
City of Hope Comprehensive Cancer Treatment Center in California
Disrupting metabolic adaptations in breast-to-brain metastases
Alana Welm, PhD
Test the value of tumorgrafts in predicting response to therapy.
ANDREA M. MASTRO, PhD
The Pennsylvania State University
Dormancy or growth? A three dimensional in vitro system to study breast cancer metastases in bone
Danny Welch, PhD
University of Kansas Cancer Center
KISS1 prevents seeded cancer cells from growing into full blown metastases
